726 / 1631
30
INV-assessed PFS in the FL population
*Stratified analysis; stratification factors: prior therapies, refractory type, geographical region
G-B,
n=164
B,
n=171
Pts with event,
n (%)
93 (56.7)
125 (73.1)
Median PFS
(95% CI), mo
25.3
(17.4, 36.0)
14.0
(11.3, 15.3)
HR (95% CI),
p-value*
0.52 (0.39, 0.69),
p<0.0001
Median follow-up (FL): 31.2 months
(vs 21.1 months in primary analysis)
Kaplan-Meier plot of INV-assessed PFS by
treatment arm (FL)
No. of patients at risk
B
G-B
0.8
0.6
0.4
0.2
0
1.0
Probability
84
107
45
86
32
67
18
49
15
40
9
26
141
138
171
164
Time (months)
12 18 24 30 36 42 48
60
6 0
B (n=171)
G-B (n=164)
Censored
+
54
4
15
0
4
0
0