727 / 1631
31
OS in the FL population
NR, not reached
*Stratified analysis; stratification factors: prior therapies, refractory type, geographical region
G-B,
n=164
B,
n=171
Pts with event,
n (%)
39 (23.8)
64 (37.4)
Median OS
(95% CI), mo
NR
(NR, NR)
53.9
(40.9, NR)
HR (95% CI),
p-value*
0.58 (0.39, 0.86),
p=0.0061
Kaplan-Meier plot of OS by
treatment arm (FL)
Median follow-up (FL): 31.2 months
(vs 21.1 months in primary analysis)
No. of patients at risk
B
G-B
0.8
0.6
0.4
0.2
0
1.0
Probability
137
141
122
129
103
111
84
90
65
71
49
56
159
147
171
164
Time (months)
12 18 24 30 36 42 48
66
6 0
B (n=171)
G-B (n=164)
Censored
+
54
32
38
7
12
60
13
20
0
0