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JULIET: Study design (Novartis)

A longer than expected period between enrolment and infusion occurred due to manufacturing delays

a

To be completed 2 to 14 days prior to tisagenlecleucel infusion

b

Infusion conducted on an in- or outpatient basis at investigator discretion

Pts eligible after ≥2

lines chemotherapy,

ineligible for or failed

auto-SCT

CD19 4-1BB, first approved CAR-T (child +TYA) B-ALL