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JULIET: Response rates

Durability of responses is shown by the stability between 3 and 6 month

response rates

Response at 3 months is indicative of the long term benefit of this treatment

Response rate, %

Best overall response

rate

(N=81)

Response at 3 months

(n=81)

Response at 6 months

(n=46)

ORR (CR + PR)

53*

38

37

CR

40

32

30

PR

14

6

7

*

P

<0.0001 (95% CI, 42-64%). Null hypothesis of ORR ≤20%