863 / 1631
There is clear heterogeneity in clinical outcomes
Ziepert at al. J Clin
Oncol
28:2373-2380.
Age adjusted IPI
Stage
LDH
Performance status
IPI
Age greater than 60 years
Stage III or IV disease
Elevated serum LDH
ECOG > 2
More than 1 extranodal site