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Lenalidomide

Chanan-Khan, A. A. et al. J Clin Oncol; 26:1544-1552 2008

Immunomodulatory properties

Modulation of both cellular and

cytokine tumour cell

microenvironment

Activates T cell and NK response

to tumour cell

Down regulates pro-survival

cytokines

Enhanced ADCC activity with

rituximab