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122
Biophysical Society 59
th
Annual Meeting, Baltimore, Maryland
Intrinsically Disordered Proteins (IDP) and
Aggregates III (Boards B71-B94)
1934-P
os
B
oard
B71
SECONDARY METAL BINDING TO AMYLOID-BETA MONOMER
IS INSIGNIFICANT UNDER SYNAPTIC CONDITIONS. Thomas
Branch, Mauricio Barahona,
Liming Ying
1935-P
os
B
oard
B72
GAS-PHASE CONFORMATIONS OF A HUNTINGTIN
N-TERMINAL PEPTIDE REVEAL CONDENSED-PHASE
HETEROGENEITY WITH AND WITHOUT THE PRESENCE OF
A PPII HELIX.
James R. Arndt
, Samaneh G. Kondalaji, Olivia Sarver,
Megan M. Maurer, Arlo Parker, Justin Legleiter, Stephen J. Valentine
1936-P
os
B
oard
B73
HUNTINGTIN N-TERMINAL FRAGMENT FIBRILS HAVE
A RIGID AMYLOID CORE FLANKED BY NON-AMYLOID
DOMAINS WITH INCREASED DYNAMICS. Cody L. Hoop, Hsiang-
Kai Lin, Karunakar Kar, Ronald Wetzel,
Patrick C A van der Wel
1937-P
os
B
oard
B74
INITIATING POLYGLUTAMINE AGGREGATION ---
COMPUTATIONAL CLARIFICATION OF THE STRUCTURAL
DETAILS.
Markus S. Miettinen
, Luca Monticelli, Praveen Nedumpully-
Govindan, Volker Knecht, Zoya Ignatova
1938-P
os
B
oard
B75
international
travel awardee
THE ROLE OF STRUCTURAL DYNAMICS IN DETERMINING
THE PRION STRAIN DIVERSITY.
Dominic Narang
, Anup K.
Srivastava, Samrat Mukhopadhyay
1939-P
os
B
oard
B76
education
travel awardee
AMYLOIDOGENICITY OF IMMUNOGLOBULIN LIGHT
CHAINS.
Kathrin Andrich
, Ute Hegenbart, Stefan Schönland, Erich
Wanker, Jan Bieschke
1940-P
os
B
oard
B77
PREDICTION OF THE EFFECTS OF THE VAL66MET
POLYMORPHISM AND ADJACENT STRUCTURED
DOMAINS ON THE CONFORMATIONAL ENSEMBLE OF AN
INTRINSICALLY DISORDERED PROTEIN, BRAIN-DERIVED
NEUROTROPHIC FACTOR.
Ruchi Lohia
, Reza Salari, Grace
Brannigan
1941-P
os
B
oard
B78
STRUCTURAL STABILITY OF DIABETES-RELATED AMYLIN
PROTOFILAMENTS: APPLICATIONS TO FIBRIL DESIGN.
Ye
Yuan
, Bartlomiej Tywoniuk, Nicolae-Viorel Buchete
1942-P
os
B
oard
B79
EXPLOSIVE FIBRILLATION KINETICS OF TWO-CHAIN
INSULIN FRAGMENT RELEASED UPON PARTIAL DIGESTION
WITH PEPSIN.
Wojciech Dzwolak
, Marcin Piejko, Robert Dec,
Viktoria Babenko, Agnieszka Hoang, Monika Szewczyk, Pawel Mak
1943-P
os
B
oard
B80
ELUCIDATING THE ROLE OF OLIGOMERS IN INSULIN
AGGREGATION USING BIOPHYSICAL METHODS.
Matthew T. Mawhinney
, Brigita Urbanc
1944-P
os
B
oard
B81
DMSO INDUCED BREAKING UP OF INSULIN FIBRILS
MONITORED BY VIBRATIONAL CIRCULAR DICHROISM.
Ge Zhang
, Viktoria Babenko, Wojciech Dzwolak, Timothy A. Keiderling
1945-P
os
B
oard
B82
education
travel awardee
THE INTRINSICALLY DISORDERED TERMINI OF ZDHHC
S-PALMITOYLTRANSFERASES FACILITATE MULTIPLE
REGULATORY FUNCTIONS.
Krishna D. Reddy
, Jeremy D. Baker,
Bin Xue, Robert J. Deschenes, Vladimir N. Uversky
1946-P
os
B
oard
B83
PROTEIN DISORDER IN DYNEIN REGULATION BY DYNACTIN
AND NUDE.
Jing Jie
, Elisar Barbar
1947-P
os
B
oard
B84
A FUZZY DNA BINDING REGION IN MBD2 RECRUITS THE
HISTONE DEACETYLASE CORE COMPLEX OF NURD AND
MODIFIES KINETICS OF DNA BINDING.
David C. Williams
,
Megha Desai, Gordon D. Ginder
1948-P
os
B
oard
B85
C/EBP
β
: CASE STUDY FOR THE IMPORTANCE OF INTRINSIC
DISORDER FOR PROTEIN FUNCTION.
Maria Miller
1949-P
os
B
oard
B86
STRUCTURAL AND DYNAMIC ANALYSIS ON DISORDERED
H4 HISTONE TAIL BY MODIFIED AWSEM-MD.
Hao Wu
, Garegin
Papoian
1950-P
os
B
oard
B87
THE ACETYLATION LANDSCAPE OF THE H4 HISTONE
TAIL.
David Winogradoff
, Ignacia Echeverria, Garegin Papoian
1951-P
os
B
oard
B88
COMPARING SOLUTION STRUCTURES OF AMYLIN AND
CGRP BY NANOSECOND LASER-PUMP SPECTROSCOPY AND
ATOMISTIC SIMULATIONS. Sara M. Sizemore, Gül H. Zerze,
Stephanie M. Cope, Jeetain Mittal,
Sara M. Vaiana
1952-P
os
B
oard
B89
PRIMARY SEQUENCE CONTROLS THE SPECIFICITY AND
AFFINITY OF A SMALL MOLECULE BINDING TO THE
INTRINSICALLY DISORDERED PROTEIN C-MYC.
Lisette M. Fred
, Kaitlyn P. Gerhart, Bethany L. Zablotsky, Scott A.
Barnett, Steven J. Metallo
1953-P
os
B
oard
B90
INTERACTION OF THE INTRINSICALLY DISORDERED C-MYC
ONCOPROTEIN WITH RACEMIC AND ENANTIOPURE SMALL
MOLECULES.
Kaitlyn P. Gerhart
, Steven J. Metallo
1954-P
os
B
oard
B91
THE INTRINSICALLY DISORDERED C-TERMINAL TAILS
OF E.COLI SINGLE-STRANDED DNA BINDING PROTEIN
REGULATE COOPERATIVE BINDING TO SINGLE-STRANDED
DNA.
Alexander G. Kozlov
, Elizabeth Weiland, Anuradha Mittal, Vince
Waldman, Rohit V. Pappu, Lohman M. Timothy
1955-P
os
B
oard
B92
ASSESSING BINDING PERTURBATION DUE TO ARTIFICIAL
VIBRATIONAL PROBE GROUPS IN THE NUCLEOPROTEIN-
PHOSPHOPROTEIN COMPLEX OF THE NIPAH VIRUS.
Rebecca B. Wai
, Shana R. Burstein, Sara K. Hess, Jenny Erales, Sonia
Longhi, Casey H. Londergan
1956-P
os
B
oard
B93
CLAWS, DISORDER, AND CONFORMATIONAL
DYNAMICS OF THE C TERMINAL REGION OF HUMAN
DESMOPLAKIN.
Charles E. McAnany
, Cameron Mura