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128

Biophysical Society 59

th

Annual Meeting, Baltimore, Maryland

2077-P

os

B

oard

B214

MOLECULAR DYNAMICS STUDIES OF LIPID I AND LIPID II IN

VARIOUS OF LIPID BILAYER ENVIRONMENTS.

Seonghoon Kim

,

Wonpil Im

2078-P

os

B

oard

B215

EICOSAPENTAENOIC ACID-CONTAINING MEMBRANE

DOMAIN INVOLVED IN CELL DIVISION OF A COLD-ADAPTED

BACTERIUM.

Jun Kawamoto

, Nobuyoshi Esaki, Tatsuo Kurihara

2079-P

os

B

oard

B216

STRONG H-BONDS FORM BILAYERS: OCHROMONAS DANICA

IS AN EXTREME EXAMPLE.

Thomas H. Haines

2080-P

os

B

oard

B217

CHOLESTEROL FLIP-FLOP AND LACK OF SWELLING IN

STRATUM CORNEUM LIPID BILAYERS.

Peter Olmsted

, Chinmay

Das, Massimo Noro

2081-P

os

B

oard

B218

HYDRATION AND SUPRAMOLECULAR ORGANIZATION

STUDIES OF LAMELLAR BODIES IN A549 LUNG CELLS USING

LAURDAN FLUORESCENCE.

Leonel S. Malacrida

, Soledad Astrada,

Mariela Bolatti, Arturo Briva, Luis A. Bagatolli

2082-P

os

B

oard

B219

MODULATION OF PHOSPHOINOSITIDE MONOLAYER

COMPRESSIBILITIES BY PHYSIOLOGICAL LEVELS OF

CA

2+

.

Adolphe Kazadi Badiambile

, Martin B. Forstner

2083-P

os

B

oard

B220

PROTON PERMEATION THROUGH EXTREMOPHILE-INSPIRED

LIPID MEMBRANES.

Thomas B. H. Schroeder

, Kathryn N. Haengel,

Mitchell A. Johnson, Claire L. Wang, Geoffray Leriche, Takaoki Koyanagi,

Jerry Yang, Michael Mayer

2084-P

os

B

oard

B221

VIBRATIONAL SPECTROSCOPIC STUDIES PROBING

CARDIOLIPIN CONTAINING LIPOSOMES WITH AND

WITHOUT CYTOCHROME C BOUND TO ITS ANIONIC

SURFACE.

Dzmitry Malyshka

, Leah Pandiscia, Reinhard Schweitzer-

Stenner

2085-P

os

B

oard

B222

DROPLET INTERFACE BILAYER AS CELL MEMBRANE MIMICS:

WATER PERMEABILITY STUDIES.

Sunghee Lee

2086-P

os

B

oard

B223

COMPARISON OF REACTIVE OXYGEN SPECIES PRODUCTION

ACTIVITY AND BINDING ABILITY OF PORPHYRINS IN CELL

MEMBRANE MODELS.

Barnabás Bőcskei-Antal

, Bianka Nagy, Szilvia

Anikó Tóth, Nikoletta Kósa, István Voszka, Gabriella Csík, Levente

Herényi

Membrane Receptors and Signal

Transduction III (Boards B224-B245)

2087-P

os

B

oard

B224

INVESTIGATING THE EFFECT OF SODIUM AND VOLTAGE ON

δ

-OPIOID RECEPTORS.

Owen N. Vickery

, Daniel T. Baptista-Hon,

Daniel Seeliger, Tim G. Hales, Ulrich Zachariae

2088-P

os

B

oard

B225

STRUCTURE-GUIDED DISCOVERY OF POSITIVE ALLOSTERIC

MODULATORS OF THE MU-OPIOID RECEPTOR.

Paola Bisignano

, Neil T. Burford, Samuel W. Gerritz, Andrew Alt, Marta

Filizola

2089-P

os

B

oard

B226

BINDING POCKETS AND POSES OF ALLOSTERIC

MODULATORS OF OPIOID RECEPTORS IDENTIFIED BY

METADYNAMICS.

Yi Shang

, Holly R. Yeatman, Neil Burford,

Kathryn Livingston, Paola Bisignano, John Traynor, Andrew Alt, Arthur

Christopoulos, Meritxell Canals, Marta Filizola

2090-P

os

B

oard

B227

STRUCTURAL DYNAMICS AND ENERGETICS UNDERLYING

ALLOSTERIC INACTIVATION OF A GPCR: INSIGHTS GAINED

FROM SITE-DIRECTED FLUORESCENCE LABELING (SDFL)

STUDIES OF THE CANNABINOID RECEPTOR CB1. Jonathan Fay,

David L. Farrens

2091-P

os

B

oard

B228

OPTIMIZATION OF SYNTHETICALLY NOVEL AGONISTS OF

THE PUTATIVE CANNABINOID RECEPTOR, GPR55, USING AN

ACTIVATED STATE MODEL.

Mary A. Lingerfelt

, Pingwei Zhao, Lara

Fakhouri, Mary E. Abood, Mitchell P. Croatt, Patricia H. Reggio

2092-P

os

B

oard

B229

SIGNALING THROUGH HOMOMERIC AND HETEROMERIC

DOPAMINE D2 AND CANNABINOID CB1 RECEPTORS.

Guoqing Xiang

2093-P

os

B

oard

B230

PHARMACOLOGICAL IMPLICATIONS OF A2AR-D2R

HETEROMERIZATION AND THE SIGNIFICANCE FOR

PARKINSON’S DISEASE.

Candice Hatcher-Solis

, Diomedes E.

Logothetis

2094-P

os

B

oard

B231

STRUCTURAL BASIS FOR THE ALLOSTERIC PHARMACOLOGY

OF SB269652 IN DOPAMINE D2 RECEPTOR.

Mayako Michino

,

Christopher J. Draper-Joyce, Prashant Donthamsetti, Jonathan A. Javitch,

J. Robert Lane, Lei Shi

2095-P

os

B

oard

B232

CROSS-SIGNALING BETWEEN THE METABOTROPIC

GLUTAMATE RECEPTOR 2 AND THE SEROTONIN 2A

RECEPTOR IN HEK-293 CELLS.

Lia Baki

, Jason Younkin, Jose Miguel

Eltit, Miguel Fribourg, Amr Ellaithy, Gyu Park, Zhanna Vysotskaya,

Diomedes E. Logothetis

2096-P

os

B

oard

B233

A POSITIVE ALLOSTERIC MODULATOR OF THE

METABOTROPIC GLUTAMATE 2 RECEPTOR ALTERS 5-HT2A

RECEPTOR SIGNALING IN A HETEROMERIC COMPLEX.

Amr Ellaithy

, Jason Younkin, Lia Baki, Diomedes Logothetis

2097-P

os

B

oard

B234

ASSEMBLY AND COOPERATIVITY OF METABOTROPIC

GLUTAMATE RECEPTORS.

Josh Levitz

, Reza Vafabakhsh, Shashank

Bharill, Shashank Bharill, Ehud Y. Isacoff

2098-P

os

B

oard

B235

GLYCAN-BASED CONNECTIVITY REGULATES THE

HIERARCHICAL ORGANIZATION OF MEMBRANE RECEPTORS

BY COUPLING THEIR MICRO- AND NANO-SCALE LATERAL

MOBILITY. Juan A. Torreno-Pina, Bruno Castro, Alessandra Cambi,

Carlo Manzo,

Maria Garcia-Parajo

2099-P

os

B

oard

B236

THE ROLE OF LIGAND DENSITY IN THE BINDING OF VON

WILLEBRAND FACTOR BY THE GLYCOPROTEIN IB-IX-V

COMPLEX IN PLATELETS.

Zeinab Al-Rekabi

, Shirin Feghhi, Nikita

Taparia, Adam D. Munday, Wendy E. Thomas, Jose A. Lopez, Joachim P.

Spatz, Nathan J. Sniadecki