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132

Biophysical Society 59

th

Annual Meeting, Baltimore, Maryland

2171-P

os

B

oard

B308

THE KINETIC PROPERTIES OF THE HUMAN GLYCINE

RECEPTOR IN RESPONSE TO DIFFERENT AGONISTS.

Elliot J. Hurdiss

, Timo Greiner, Rilei Yu, Phillip C. Biggin, Lucia G.

Sivilotti

2172-P

os

B

oard

B309

EVOLUTION OF PRO-LOOP CHANNELS: A FRESH LOOK AT

THE FORMER CYS-LOOP FAMILY. Mariama Jaiteh, Antoine Taly,

Jérôme Hénin

2173-P

os

B

oard

B310

ELECTROMAGNETIC FIELDS INHIBIT CYS-LOOP RECEPTOR

FUNCTION BY INDUCING A NOVEL CONFORMATIONAL

STATE. Fernanda Tolosa, Walter R. Cravero,

Cecilia B. Bouzat

2174-P

os

B

oard

B311

SUPER-RESOLUTION IMAGING AND SINGLE PARTICLE

TRACKING OF SEROTONIN 5HT3A RECEPTOR IN

BIOMIMETIC MEMBRANES.

Adam O. Barden

, Adam S. Goler,

James A. Brozik

2175-P

os

B

oard

B312

INTERACTION OF BUPROPION WITH 5-HT

3A

RECEPTORS.

Akash Pandhare

, Dominique Gagnon, Henrik Wilms,

Michael P. Blanton, Michaela Jansen

2176-P

os

B

oard

B313

EXPLORING THE GATING PATHWAY IN AN EUKARYOTIC

LIGAND-GATED ION CHANNEL.

Stephanie A. Heusser

, Ozge

Yoluk, Erik Lindahl

2177-P

os

B

oard

B314

COMPLEX MODULATION OF THE GABA

A

α

1

β

2

Γ

2 RECEPTOR

FUNCTION BY BUPROPION.

Jeremy M. Thompson

, Aneesh Pappu,

Akash Pandhare, Michaela Jansen

2178-P

os

B

oard

B315

BUILDING GABAA RECEPTORS FOR STRUCTURAL

DETERMINATION.

Duncan C. Laverty

, Adam Cryar, Konstantinos

Thalassinos, Trevor G. Smart

2179-P

os

B

oard

B316

DOPAMINE DIRECTLY MODULATES GABAA RECEPTORS.

Paul Hoerbelt

, Mark W. Fleck

2180-P

os

B

oard

B317

MMTX1 AND MMTX2 FROM CORAL SNAKE VENOM

POTENTLY MODULATE GABA(A) RECEPTOR ACTIVITY. Jean-

Pierre Rosso, Jürgen R. Schwarz, Marcelo Diaz-Bustamante, Brigitte

Céard, José María Gutiérrez, Matthias Kneussel, Olaf Pongs,

Frank Bosmans

, Pierre E. Bougis

2181-P

os

B

oard

B318

MONITORING MOTIONS IN GABA-A RECEPTOR

INTERSUBUNIT TRANSMEMBRANE CAVITIES.

Tzu-Wei Tsao

,

Borna Ghosh, Cynthia Czajkowski

Ion Channel Regulatory Mechanisms II

(Boards B319-B338)

2182-P

os

B

oard

B319

LIBERATION OF PSER68-PLM INHIBITION OF NCX1 BY AN

OPTIMIZED ANCHORING DISRUPTOR PEPTIDE.

Kjetil Hodne

,

Pimthanya Wanichawan, Tandekile Lubelwana Hafver, William Edward

Louch, Marianne Lunde, Marita Martinsen, Ole Mathias Sejersted,

Cathrine Rein Carlson

2183-P

os

B

oard

B320

THE TALK-1 C-TERMINUS IS A CHARGE-SENSITIVE MODULE

REGULATING CHANNEL ACTIVITY.

Nicholas Vierra

, Prasanna K.

Dadi, Farah Ladak, David A. Jacobson

2184-P

os

B

oard

B321

INVESTIGATING VIRAL CHANNEL FORMING PROTEIN

VPU WITH COARSE-GRAINING MOLECULAR DYNAMICS

SIMULATION.

Meng-Han Lin

, Wolfgang Fischer

2185-P

os

B

oard

B322

KIR2.1 CHANNELS COMPENSATE FOR THE LOSS OF KATP

CHANNELS IN SUR1 NULL ISLETS.

Suryakiran Vadrevu

, Jinhua

Ren, Min Zhang, Eric J. Glynn, Arthur Sherman, Leslie S. Satin

2186-P

os

B

oard

B323

SECRETED HUMAN CLCA1 ACTIVATES CALCIUM-

DEPENDENT

CHLORIDE CURRENTS VIA INTERACTION WITH TMEM16A

(ANOCTAMIN 1).

Monica Sala-Rabanal

, Zeynep Yurtsever, Colin G.

Nichols, Tom J. Brett

2187-P

os

B

oard

B324

INHIBITION OF THE CFTR CHLORIDE CHANNEL BY

SPHINGOMYELINASE.

Brandon Stauffer

, Guiying Cui, Daniel T.

Infield, Nael McCarty

2188-P

os

B

oard

B325

MOLECULAR DYNAMICS SIMULATIONS OF CALCIUM

BINDING SITES IN THE RCK DOMAIN OF THE MTHK GATING

RING.

Tangzhen Zhao

, Yukun Wang, Qin Xu, Dongqing Wei

2189-P

os

B

oard

B326

FUNCTIONAL COUPLING BETWEEN ANO1 AND TRPV1

CHANNELS IN SENSORY NEURONS. Shihab Shah,

Nikita Gamper

2190-P

os

B

oard

B327

PHOSPHOLIPASE D2 SPECIFICALLY REGULATES TREK

CHANNELS VIA DIRECT INTERACTION AND LOCAL

PRODUCTION OF PHOSPHATIDIC ACID. Yannick Comoglio,

Levitz Joshua, Michael Kienzler, Florian Lesage, Ehud Isacoff,

Guillaume Sandoz

2191-P

os

B

oard

B328

THE MODULATORY FUNCTION OF THE BK CHANNEL

Γ

1 SUBUNIT IS DETERMINED BY ITS TRANSMEMBRANE

DOMAIN. Qin Li, Jiyuan Zhang, Karren Yen,

Jiusheng Yan

2192-P

os

B

oard

B329

DIFFERENTIAL EFFECTS OF PIP2 ON SLO1 BK CHANNELS

WITH DIFFERENT AUXILIARY SUBUNITS.

Yutao Tian

, Florian

Ullrich, Rong Xu, Heinemann H. Stefan, Shangwei Hou, Toshinori Hoshi

2193-P

os

B

oard

B330

A FLUOROGEN-ACTIVATING BIOSENSOR FOR ANALYSIS OF

BK CHANNEL TRAFFIC AND SURFACE RESIDENCY.

Christopher Pratt

, Jianjun He, Alison Barth, Marcel Bruchez

2194-P

os

B

oard

B331

UNDERSTANDING THE DYNAMICS OF K2P CHANNELS IN

COMPLEX LIPID BILAYERS.

Prafulla Aryal

, Stephen J. Tucker, Mark

SP Sansom

2195-P

os

B

oard

B332

education

travel awardee

NON-MARKOVIAN PROTEIN DYNAMICS IN A NEAR-CRITICAL

MEMBRANE MODEL.

Ofer Kimchi

, Benjamin B. Machta