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130

Biophysical Society 59

th

Annual Meeting, Baltimore, Maryland

2122-P

os

B

oard

B259

STUDYING TROPONIN WITHIN REGULATED ACTIN AT

SINGLE MOLECULE RESOLUTION.

Christopher Solis-Ocampo

,

Maria E. Moutsoglou, Gi-Ho Kim, John M. Robinson

2123-P

os

B

oard

B260

OBSERVING THE PCA-FORCE RELATIONSHIP WITH A 3-BEAD

LASER TRAP ASSAY.

Thomas J. Longyear

, Sam Walcott, Edward P.

Debold

2124-P

os

B

oard

B261

ENERGY LANDSCAPES REVEAL THE MYOPATHIC EFFECTS

OF TROPOMYOSIN MUTATIONS. Marek Orzechowski, Gerrie P.

Farman, Jeffrey R. Moore, Stefan Fischer,

William Lehman

2125-P

os

B

oard

B262

ESTIMATION OF LOCAL FORCES IN MYOFILAMENTS USING

X-RAY DIFFRACTION PATTERNS AND MUSCLE MECHANICS

DATA. Momcilo Prodanovic, Djordje Nedic,

Thomas C. Irving

, Srboljub

M. Mijailovich

2126-P

os

B

oard

B263

HIERARCHY OF REGULATORY INTERACTIONS IN THE

SARCOPLASMIC RETICULUM CALCIUM TRANSPORT

COMPLEX. John E. Rubin, Bengt Svensson, Kurt C. Peterson, Seth L.

Robia, David D. Thomas,

Joseph M. Autry

2127-P

os

B

oard

B264

REGULATION OF MYOBLAST PROLIFERATION AND

DIFFERENTIATION BY ANOCTAMIN 5 AND 6.

Li Xu

, Renzhi

Han, LiXia Zhao

2128-P

os

B

oard

B265

CHARGED VESICLES POTENTLY INDUCE NLRP3

INFLAMMASOME ACTIVATION.

Lixia Zhao

, Li Xu, Zhenyu Zhong,

Yougang Zhai, Liang Qiao, Renzhi Han

2129-P

os

B

oard

B266

MITSUGUMIN 56 IS AN MBOAT FAMILY MEMBER AND

CONTRIBUTES TO POSTNATAL MUSCLE MATURATION.

Myuki Nishi

, Bo Van, Shinji Komazaki, Daiju Yamazaki, Ki-Ho Park,

Jianjie Ma, Hiroshi Takeshima

2130-P

os

B

oard

B267

SUPPRESSED AUTOPHAGY FLUX IN SKELETAL MUSCLE OF AN

AMYOTROPHIC LATERAL SCLEROSIS MOUSE MODEL.

Yajuan

Xiao

, Changling Ma, Jianxun Yi, Shaoping Wu, Guo Luo, Xiulong Xu,

Pei-Hui Lin, Jun Sun, Jingsong Zhou

2131-P

os

B

oard

B268

international

travel awardee

IMPAIRMENT IN ACETYLCHOLINE RELEASE BY

CARDIOMYOCYTES LEADS TO ENHANCED PATHOLOGICAL

HYPERTROPHY.

Cibele Rocha-Resende

, Vania Prado, Marco Prado,

Aristobolo Mendes Silva, Silvia Guatimosim

2132-P

os

B

oard

B269

MYOPATHIC CHANGES IN MURINE SKELETAL MUSCLE

LACKING SYNEMIN.

Karla Garcia-Pelagio

, Joaquin Muriel, Andrea

O´Neill, Patrick Desmond, Richard M. Lovering, Linda Lund, Meredith

Bond, Robert Bloch

2133-P

os

B

oard

B270

CYTOKINE STIMULATION INDUCES NOX2-DEPENDENT ROS

PRODUCTION AND DECREASES MUSCLE FUNCTION.

James A. Loehr

, Reem Abo-Zahrah, Rituraj Pal, George G. Rodney

Mechanisms of Voltage Sensing and

Gating (Boards B271-B291)

2134-P

os

B

oard

B271

AN EXPERIMENTALLY-VALIDATED MODEL STRUCTURE

OF THE HV1 PROTON CHANNEL VOLTAGE SENSOR IN ITS

RESTING STATE. Younes Mokrab, Ashley Bennett, Mark S. P. Sansom,

I. Scott Ramsey

2135-P

os

B

oard

B272

UNVEILING POTENTIAL BINDING SITES IN THE HV1 FOUR

HELIX BUNDLE.

Eleonora Gianti

, Lucie Delemotte, Vincenzo

Carnevale, Francesco Tombola, Douglas Tobias, Michael L. Klein

2136-P

os

B

oard

B273

ALLOSTERIC COUPLING BETWEEN OPEN SUBUNITS IN

THE HV1 PROTON CHANNEL PROBED BY GUANIDINO-

THIAZOLES.

Liang Hong

, Vikrant Singh, Heike Wulff, Francesco

Tombola

2137-P

os

B

oard

B274

CHARACTERIZATION AND SUBCELLULAR LOCALIZATION OF

HV1 IN LINGULODINIUM POLYEDRUM CONFIRMS ITS ROLE

IN BIOLUMINESCENCE.

Juan D. Rodriguez

, Saddef Haq, Kristine F.

Nowak, Deri Morgan, Vladimir V. Cherny, Steven Bernstein, Maredith S.

Sapp, John R. Curcuru, Coretha Antchouey, Scott J. Nowak, Allen Place,

Thomas E. DeCoursey, Susan M E Smith

2138-P

os

B

oard

B275

ENGINEERED VOLTAGE SENSING PHOSPHATASES: WHAT DO

THEY TELL US ABOUT THE GATING MECHANISM? Angeliki

Mavrantoni, Kirstin Hobiger, Michael G. Leitner, Dominik Oliver,

Christian R. Halaszovich

2139-P

os

B

oard

B276

education

travel awardee

THE ROLE OF THE C2 DOMAIN OF VOLTAGE SENSING

PHOSPHATASE (VSP).

Kevin D. Zolman

, Paul M. Castle, Susy C.

Kohout

2140-P

os

B

oard

B277

INVESTIGATING THE FUNCTION OF A NOVEL VOLTAGE-

SENSING PROTEIN.

Erika Babikow

, Ferenc Papp, Suvendu Lomash,

Jamie Smith, Kenton Swartz

2141-P

os

B

oard

B278

education

travel awardee

PUTATIVE VOLTAGE SENSITIVE ENZYMES IN

PROKARYOTES.

Joshua P. Clark

, Susan M. E. Smith

2142-P

os

B

oard

B279

SEQUENCE SIGNATURE OF VOLTAGE SENSING DETECTED

VIA DIMENSIONALITY REDUCTION TECHNIQUES.

Daniele Granata

, Matteo Marsili, Michael L. Klein, Vincenzo Carnevale

2143-P

os

B

oard

B280

LIPID-DEPENDENT CONFORMATIONAL TRANSITIONS IN

KVAP ARE DRIVEN BY VOLTAGE SENSING DOMAIN.

Qufei Li

,

Julia Skalska, Sherry Wanderling, Eduardo Perozo

2144-P

os

B

oard

B281

MOLECULAR DETERMINANTS OF TEMPERATURE

DEPENDENT GATING OF ION CHANNELS.

Sandipan Chowdhury

, Brian W. Jarecki, Baron Chanda

2145-P

os

B

oard

B282

THE GATING CHARGE OF KV1.2 IS LESS THAN EXPECTED

FROM ITS SIMILARITY TO SHAKER.

Itzel G. Ishida

, Gisela E.

Rangel-Yescas, Leon D. Islas