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134
Biophysical Society 59
th
Annual Meeting, Baltimore, Maryland
2221-P
os
B
oard
B358
EFFECTS OF THE CONNEXIN43 CT ON GAP JUNCTION
SUB-DOMAIN ORGANIZATION AND MYOCYTE-FIBROBLAST
INTERACTIONS IN THE INJURY BORDER ZONE.
Emily L. Ongstad
, Robert G. Gourdie
2222-P
os
B
oard
B359
MOLECULAR DYNAMICS OF SELECTIVE SUGAR PERMEATION
THROUGH THE CONNEXIN26 CHANNEL. Lyna Luo, Angelo R.
Rossi,
Andrew L. Harris
2223-P
os
B
oard
B360
THE RESIDUES IN THE FIRST EXTRACELLULAR DOMAIN
PLAY AN IMPORTANT ROLE IN TRANSJUNCTIONAL-
VOLTAGE DEPENDENT GATING AND UNITARY CHANNEL
CONDUCTANCE OF CX50 GAP JUNCTION CHANNELS. Xiaoling
Tong, Hiroshi Aoyama, Swathy Sudhakar, Honghong Chen,
Donglin Bai
2224-P
os
B
oard
B361
RESIDUES INVOLVED IN CX26 HEMICHANNELS VOLTAGE
DEPENDENT GATING.
Bernardo I. Pinto
, David Baez-Nieto,
Amaury Pupo, Agustin Martinez, Ramon Latorre, Carlos Gonzalez
2225-P
os
B
oard
B362
UNDERSTANDING THE CONFORMATIONAL DYNAMICS OF
THE PORIN OCCK5.
Karunakar Reddy Pothula
2226-P
os
B
oard
B363
CYCLODEXTRIN INTERACTION WITH SPECIFIC CHANNEL
CYMA FROM K. OXYTOCA.
Satya Prathyusha Bhamidimarri
, Jing
Lu, Jigneshkumar Dahyabhai Prajapati, Ivan Barcena Uribarri, Bert van
den Berg, Ulrich Kleinekathoefer, Mathias Winterhalter
2227-P
os
B
oard
B364
MIMICKING BIOLOGY WITH NANOMATERIALS: CARBON
NANOTUBE PORINS IN LIPID MEMBRANES.
Aleksandr Noy
2228-P
os
B
oard
B365
UNDERSTANDING THE TRANSLOCATION OF
FLUOROQUINOLONES THROUGH OMPC USING THE
METADYNAMICS.
Jigneshkumar D. Prajapati
, Harsha Bajaj, Matteo
Ceccarelli, Mathias Winterhalter, Ulrich Kleinekathöfer
2229-P
os
B
oard
B366
SINGLE-MOLECULE DETECTION OF INSERTION AND
FOLDING OF OMPA IN DROPLET INTERFACE BILAYERS.
Eve E. Weatherill
, David P. Marshall, Mark I. Wallace
Cardiac Muscle Mechanics and Structure II
(Boards B367-B386)
2230-P
os
B
oard
B367
FROM MOLECULE TO ORGAN: A MULTISCALE SIMULATOR
OF HEART CONTRACTION.
Lorenzo Marcucci
, Toshio Yanagida,
Takumi Washio
2231-P
os
B
oard
B368
SUBSTRATE STIFFNESS-MODULATED REGISTRY PHASE
CORRELATIONS IN CARDIOMYOCYTES MAPS STRUCTURAL
ORDER TO COHERENT BEATING.
Kinjal Dasbiswas
, Stephanie J.
Majkut, Dennis E. Discher, Samuel A. Safran
2232-P
os
B
oard
B369
international
travel awardee
REGULATION OF CARDIOMYOCYTE T-TUBULE
ORGANIZATION AND DENSITY BY VENTRICULAR WALL
STRESS.
Marianne Ruud
, Michael Frisk, Per Andreas Norseng, Åsmund
Treu Røe, Emil Espe, Jan Magnus Aronsen, Ivar Sjaastad, Ole M.
Sejersted, Geir Arve Christensen, William Edward Louch
2233-P
os
B
oard
B370
COMPUTATIONAL MODEL OF CROSS-BRIDGE CYCLING
AND FORCE GENERATION TO EXPLAIN THE EFFECT OF
METABOLITES ON CARDIAC MUSCLE MECHANICS.
Shivendra Tewari
, Scott Bugenhagen, Bradley Palmer, Daniel Beard
2234-P
os
B
oard
B371
FROM CONTRACTILE NON-UNIFORMITIES AND
MECHANICAL INSTABILITIES TO HYPERTROPHIC
CARDIOMYOPATHY.
Alf Mansson
2235-P
os
B
oard
B372
OXIDATIVE STRESS REGULATES TITIN ELASTICITY BY
AFFECTING IG-DOMAIN STABILITY.
Nazha Hamdani
, Jorge
Alegre-Cebollada, Martin Breitkreuz, Lars Leichert, Julio M. Fernandez,
Wolfgang A Linke
2236-P
os
B
oard
B373
AB-CRYSTALLIN BINDS TO TITIN IG DOMAINS
AND INCREASES STIFFNESS OF SKINNED CARDIAC
TRABECULAE.
Cameron W. Turtle
, Georg Hochberg, Henrik Müller,
Katja Gehmlich, Andrew Baldwin, Charles Redwood, Justin Benesch
2237-P
os
B
oard
B374
STRUCTURAL THERMODYNAMICS AND KINETICS OF THE
CARDIAC MYOSIN/OMECAMTIV MECARBIL COMPLEX
REVEALED BY TIME-RESOLVED FRET.
John Rohde
, Daniel O.
Johnsrud, Sinziana Cornea, Kurt C. Peterson, Gregory D. Gillispie, David
D. Thomas, Joseph M. Muretta
2238-P
os
B
oard
B375
IMPACT OF OMECAMTIV MECARBIL ON HUMAN
β
-CARDIAC
MYOSIN STRUCTURE AND FUNCTION.
Anja M. Swenson
,
Howard D. White, Christopher M. Yengo
2239-P
os
B
oard
B376
THE R146N AND R249Q MYOSIN MUTATIONS DISRUPT
MOTOR FUNCTION AND MYOFIBRILLAR STRUCTURE AND
CAUSE CARDIOMYOPATHY IN DROSOPHILA.
Meera Cozhimuttam Viswanathan
, William Kronert, Girish Melkani,
Anju Melkani, Anthony Cammarato, Sanford Bernstein
2240-P
os
B
oard
B377
EFFECTS OF HYPERTROPHIC CARDIOMYOPATHY CAUSING
R403Q MUTATION ON HUMAN BETA-CARDIAC MYOSIN
BIOMECHANICAL FUNCTION: SINGLE MOLECULE TO
ENSEMBLE STUDIES.
Suman Nag
, Ruth Sommese, Shirley Sutton,
Kathleen Ruppel, James Spudich
2241-P
os
B
oard
B378
CHARACTERIZATION OF
α
-TROPOMYOSIN (TM) MUTANTS
THAT CAUSE HYPERTROPHIC CARDIOMYOPATHY (HCM) IN
HUMANS: IN VITRO MOTILITY ASSAYS WITH A MICROSCOPIC
HEAT PULSE.
Shuya Ishii
, Kotaro Oyama, Madoka Suzuki, Masataka
Kawai, Shin’ichi Ishiwata
2242-P
os
B
oard
B379
PEPTIDE MODULATION OF MYOSIN COILED COIL
STABILITY MONITORED WITH OPTICAL AND FORCE
SPECTROSCOPY.
James W. Dunn
, Michael Bih, Rohit Singh, Douglas
D. Root
2243-P
os
B
oard
B380
ENHANCED TROPONIN-I BINDING EXPLAINS THE
FUNCTIONAL CHANGES PRODUCED BY THE HYPERTROPHIC
CARDIOMYOPATHY A8V MUTATION OF CARDIAC
TROPONIN-C.
Clara A. Michell
, Jose R. Pinto, Javier E. Hasbun,
Henry G. Zot