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99

Biophysical Society 59

th

Annual Meeting, Baltimore, Maryland

M

O

N

D

A

Y

1597-P

os

B

oard

B548

MAPPING FUNCTIONAL GROUP REQUIREMENTS OF

LIGANDS AT THE OCCLUDED BINDING POCKET OF

β

2-

ADRENERGIC G-PROTEIN COUPLED RECEPTOR USING SITE

IDENTIFICATION BY LIGAND COMPETITIVE SATURATION

SIMULATIONS.

Sirish K. Lakkaraju

, Wenbo Yu, Prabhu E. Raman,

Alexander D. MacKerell Jr.

1598-P

os

B

oard

B549

INSIGHTS FROM ALL-ATOM MOLECULAR DYNAMICS

SIMULATIONS OF 40 NUCLEOSOME CHROMATIN

FIBER.

Ramu Anandakrishnan

, Saeed Izadi, Alexey V. Onufriev

1599-P

os

B

oard

B550

COMPUTATIONALLY PROJECTING THE INFLUENCE OF

NUCLEIC ACID ON PATHWAYS OF NUCLEATION-LIMITED

VIRUS CAPSID ASSEMBLY.

Gregory R. Smith

, Lu Xie, Russell

Schwartz

1600-P

os

B

oard

B551

DOCKING TO THE HIGHLY FLEXIBLE ESTROGEN RECEPTOR

LIGAND BINDING DOMAIN VIA MIXED-RESOLUTION

MONTE CARLO.

Sundar Raman Subramanian

, Daniel M. Zuckerman

1601-P

os

B

oard

B552

TOWARDS THE SIMULATION OF A COMPLETE ATP

SYNTHASE: UNRAVELLING THE STRUCTURAL BASIS OF THE

ENZYME’S REVERSIBLE ACTION.

Abhishek Singharoy

, Klaus

Schulten

1602-P

os

B

oard

B553

SIN MUTATIONS ALTER STRUCTURE AND DYNAMICS OF

HUMAN MONONUCLEOSOMES.

Suma Mohan S

, Thomas C.

Bishop, Vijayalakshmi Mahadevan

1603-P

os

B

oard

B554

QUINONE BINDING IN BACTERIAL PHOTOSYNTHETIC

REACTION CENTER.

Arpita Banerjee

, Marilyn Gunner

1604-P

os

B

oard

B555

MOLECULAR DYNAMIC SIMULATION STUDIES ON LOLA

AND LOLB PROTEINS IN E.COLI.

Priyadarshini Murahari

, Gautam

Pennathur, Sharmila Anishetty

1605-P

os

B

oard

B556

THE ROLE OF THE ION DEHYDRATION PROCESS IN LOW

AND HIGH CONDUCTANCE K CHANNELS.

Romina V.

Sepúlveda

, Felipe Bravo-Moraga, Ignacio Diaz-Franulic, Daniel Aguayo,

David Naranjo, Ramon Latorre, Fernando D. Gonzalez-Nilo

1606-P

os

B

oard

B557

COMPUTATIONAL DESIGN OF ALLOSTERIC INHIBITORS OF

AKT AND SGK KINASES.

D. S. Dalafave

, R. E. Dalafave

Optical Microscopy and Super-Resolution

Imaging I (Boards B558-B586)

1607-P

os

B

oard

B558

AN AUTOMATED PROTOCOL FOR PERFORMANCE

BENCHMARKING A WIDEFIELD FLUORESCENCE

MICROSCOPE.

Michael Halter

, Elianna Bier, Paul C. DeRose, Gregory

A. Cooksey, Steven J. Choquette, Anne L. Plant, John T. Elliott

1608-P

os

B

oard

B559

RESPIRATION RATE MEASUREMENTS OF SINGLE BACTERIAL

CELLS.

Michael C. Konopka

1609-P

os

B

oard

B560

DEVELOPMENT OF PHYSIOLOGICALLY BASED

PHARMACOKINETIC MODEL (PBPK) OF CANCER

TREATMENT IN MICE.

Jeremy C. Bonor

1610-P

os

B

oard

B561

RAISING THE SPEED LIMIT ON 3D-3WAY FRET

MICROSCOPY.

Brandon L. Scott

, Adam D. Hoppe

1611-P

os

B

oard

B562

STRETCHED, ORIENTED DNA ARRAYS (SODA) FOR

FLUORESCENCE BASED SINGLE-MOLECULE EXPERIMENTS

IN COMPLEX ENVIRONMENT.

Eugeniu Ostrofet

, Seungkyu Ha,

Richard Janissen, Theo van Laar, Nynke Dekker

1612-P

os

B

oard

B563

DUAL-SWITCHING FRET (DSFRET) IMAGING BASED ON

PHOTOSWITCHABLE DONOR-ACCEPTOR PAIR.

Yingqi Wang

, Ji

Tang, Xiaodong Liu

1613-P

os

B

oard

B564

DYNAMIC TURNOVER OF FTSZ-RING IN LIVE CELL.

Xinxing Yang

, Christopher Herrick Bohrer, Jie Xiao

1614-P

os

B

oard

B565

COUNTING MOLECULES IN NON-MUSCLE MYOSIN II

FILAMENTS.

Xiaohu Wan

1615-P

os

B

oard

B566

Z-PROFILING OF CFTR OLIGOMERIZATION STATE

DISTRIBUTIONS VIA SINGLE MOLECULE STEP

PHOTOBLEACHING ANALYSIS IN EPITHELIAL CELLS.

Jean-Francois Desjardins

, Asmahan Abu-Arish, Amani Hariri, Hanadi F.

Sleiman, Gonzalo Cosa, John W. Hanrahan, Paul W. Wiseman

1616-P

os

B

oard

B567

DIMERIZATION OF EPHA2 IN CELL MEMBRANES.

Deo R. Singh

, Chris King, Nisha R. Gupta, Matt Salotto, Kalina

Hristova

1617-P

os

B

oard

B568

SINGLE MOLECULE ANALYSIS REVEALS COEXISTENCE

OF STABLE SEROTONIN TRANSPORTER MONOMERS AND

OLIGOMERS IN THE LIVE CELL PLASMA MEMBRANE. Andreas

Anderluh, Enrico Klotzsch, Vivek Kumar, Amy H. Newman, Harald H.

Sitte,

Gerhard J. Schuetz

1618-P

os

B

oard

B569

RFP TAGS FOR LABELING SECRETORY PATHWAY

PROTEINS.

Mingshu Zhang

, Xi Zhang, Lin Yuan, Pingyong Xu

1619-P

os

B

oard

B570

“DECORATING” CELLS WITH GENETICALLY ENCODED

FLUORESCENT PROTEINS - WHAT COLOR SUITS YOUR

EXPERIMENT BEST?

Li-Chun Tu

, Juahdi Monbo, Aviva Joseph, David

Grunwald

1620-P

os

B

oard

B571

CONFOCAL ABSORPTION MICROSCOPY OF BIOMOLECULES

IN THE ATTO-MOLE RANGE.

Alfons Schulte

, Fatholah Salehi,

Michael Sigman

1621-P

os

B

oard

B572

TESTING A DIFFUSION TRAP MODEL FOR STORE-OPERATED

CALCIUM ENTRY BY SINGLE PARTICLE TRACKING.

Minnie M. Wu

, Elizabeth D. Covington, Richard S. Lewis