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S987

ESTRO 36 2017

_______________________________________________________________________________________________

requires a dose limitation in healthy organs at risk

(contralateral lung, heart, spine)

Our

objectives

were:

-- To evaluate the mean dose (Dm) received by the

contralateral lung in SBRT for thoracic lesions.

-- To analyze if PTV volume and/or total dose (TD) are

related to the Dm achieved

in the contralateral lung.

Material and Methods

A total of 26 pulmonary lesions treated with SBRT were

evaluated. Simulation was performed with CT 4D

respiratory gating and customized immobilization devices.

PTV was designed with an isotropic margin of 0.5 cm from

the GTV. Treatment was delivered with Linear Accelerator

( CLINAC, Varian), and verification done with internal

fiducial markers surrogates.

Results

Total Dose (TD) (Gy): range 20 – 45 Gy. Most cases (18;

69%) received a TD of

45Gy.

Dose/fraction: range 10-20 Gy/fr. The most frequent

fractionation was 15 Gy (20; 77%).

PTV volumen (cc): range between 10.18 - 99.33cc, with a

mean: 36.14cc ; median:

26.65cc

Healthy lung Dm (Gy): range 0.23 - 9.8 Gy; mean: 1.75Gy;

median: 1.25Gy

The increase in PTV volume did not associate an increase

in the average dose to the contralateral lung. Fig 1

An increase in total dose not involved an associated

increase in the dose to the healthy lung. Fig. 2

Conclusion

The Mean Dose received by the contralateral healthy lung

is

minimal.

No relationship was found between the increase in total

dose and increased in contralateral lung Dmean

No relationship was found between the volume of PTV and

Dmean reached in contralateral

lung

The parameters PTV and TD do not appear to relate to the

dose received to the contralateral

lung.

We can conclude that SBRT technique can be applied

safely largely preserving the healthy lung.

EP-1829 Dose delivery accuracy in total body

irradiation delivered with Step and Shoot IMRT

T. Berlon

1

, L. Specht

1

, P.M. Petersen

1

, L.S. Fog

1

1

Rigshospitalet, Clinic of Oncology- Department of

Radiotheraphy, Copenhagen, Denmark

Purpose or Objective

In total body irradiation (TBI) delivered with step and

shoot IMRT (SS IMRT), the dose conformity is considerably

improved compared with the more widely used TBI

delivered with open fields. This conformity is achieved

through the use of multiple fields defined by multileaf

collimators (MLCs). We aim to quantify the accuracy with

which TBI patients treated at our clinic were positioned,

and to determine the effect any positioning errors may

have had on the delivered dose.

Material and Methods

Images acquired as a routine part of the patient treatment

with the Theraview ™ (Theraview Technology, Leuden,

The Netherlands) imaging system were used to determine

the positioning shift in the cranio-caudal direction.

Images for 11 consecutive patients, each receiving 6

fractions, were analysed and the shifts recorded (figure

1). For 3 of the patients, only images for 5 of the 6

fractions

were

available.

The plans were then recalculated implementing the shifts

using the algorithm used for the clinical plans (Eclipse ™,

Varian Medical Systems, Palo Alto, AAA algorithm, v 13.6).

The mean and maximum doses for the lungs, kidneys,

brain and the (body-lungs-5mm) structure were extracted

and the difference between the planned and the

recalculated

doses

determined.Results

The mean doses change by a maximum of 0.6% (lungs), 0.6

(kidneys), 0.5% (brain) and 0.2% (body-lungs-5mm). The

greatest difference between the maximum doses are 8.0%

(lungs), 4.8% (kidneys), 2.6% (brain) and 12.0% (bodylungs-

5mm).

The standard deviation of the difference between the

calculated and recalculated doses are greater for the

maximum doses than the mean doses (figure 2). Given that

the minimum and maximum doses for SS TBI are typically

in the range 90-110% of the prescribed dose, the

differences in maximum dose should lead to care

being

taken when positioning patients for SS TBI.

Conclusion

Patient positioning for a total of 63 fractions of SS TBI is

such that the mean delivered doses differs from the

planned by less than 0.6%. However, the maximum doses