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S115

ESTRO 36 2017

_______________________________________________________________________________________________

Purpose or Objective

Recently the 0.35T CO

60

MRIdian system (Viewray Inc.,

Cleveland) is clinically implemented at our institution.

IMRT online adaptive patient treatment is daily routine.

Quality assurance (QA) on dose delivery (both absolute and

position), and end to end test (per fraction and overall)

are prerequisites for safety and quality. Hereto, a reliable

dosimeter is required. EBT GafChromic film might

appropriate. However, a magnetic field can cause

perturbations to absolute and relative dosimetry

measurements. In addition, the amount of radiation

induced dipole polymers might be influenced by the

orientation of the film in the B

0

-field, i.e. an angular

dependency in absolute dose response might be present.

The purpose of this study is to investigate suitability of

EBT3 GafChromic film for MRIdian QA purposes.

Material and Methods

GafChromic film sheets were irradiated in a water

phantom using the MRIdian and a Linac (Varian 2300C/D,

6MV) as comparison system. The film sheets are placed in

a rotatable device positioned in the water phantom such

that the B

0

field is frontal or sagittal to the film surface in

initial position (figure 1). The film was rotated over 7

angles from 0° to 90° and irradiated with 3Gy. On each

machine 4 measurements were performed for each

orientation. The irradiation setup is 5cm depth, 100cm SSD

and 10.5x10.5cm

2

/10x10cm

2

(MRIdian/Linac) field size.

Optical density (OD) to dose (D) calibration measurements

(4x) were performed up to 8Gy both on MRIdian and Linac,

with the film perpendicular to the beam axis.

The film sheets were scanned in portrait mode with the

A4 Epson 1680 Expression Pro flatbed scanner and at the

film rotation point OD and D values were analyzed for the

red, green and blue channel.

The following comparisons were made:

a. Reproducibility of MRIdian and Linac film measurements

b. Angle dependent film response with (MRIdian) and

without B

0

(Linac) influence

c. Angle dependent film response in frontal or sagittal

setting

Results

Table 1 represents (a) the reproducibility of film OD values

for both machines, (b) the influence of B

0

on film dose

response over all angles and (c) the mean dose values

averaged over all angles for frontal and sagittal planes.

The blue channel shows the widest range, which is i.a. due

to the fact that the blue channel is barely dependent on

dose and is sensitive to the dye homogeneity in the film.

Using triple color correction on the results in (c) gives

better mutual correspondence.

Conclusion

All data indicates that there is no dose deviation between

MRIdian and Linac measurements neither in frontal or

sagittal setting. In addition, within experimental

uncertainty there is no B

0

influence on absolute film dose

response. This means that EBT3 GafChromic film can be

used for absolute dosimetry regardless its orientation in

the field. This makes it a suitable dosimeter for QA

measurements and end to end testing in a 0.35T CO

60

machine.

OC-0232 Development of a novel ‘end to end’

dosimetry audit of motion management in

radiotherapy

A.L. Palmer

1

, D. Nash

1

, S. Jafari

1

, S. Muscat

1

1

Portsmouth Hospital NHS trust, Medical Physics

Department, Portsmouth Hampshire, United Kingdom

Purpose or Objective

External dosimetry audit is valuable to assure quality,

safety, and enable improvements. However, motion

management in radiotherapy has not previously been

subject to rigorous audit. 4DCT allows assessment of

motion at treatment planning, but verifying the accuracy

of mitigation strategies at treatment planning and

delivery is poorly reported. This includes any detrimental

effect of MLC, gantry and target motion interplay. We

have developed an end-to-end dosimetry audit system to

objectively assess the success of motion management

strategies. The audit system may be used for

interdepartmental dosimetry audit as well as to provide

improved understanding and accuracy of motion managed

radiotherapy.

Material and Methods

The system uses a respiratory motion lun g-phantom

(Quasar), custom designed insert with targe t (~40 mm

diameter irregular structure) and lung OAR. Dose plane

measurement is made using triple-channel film dosimetry

(EBT3 and FilmQAPro) with uncertainty reduction

strategies. Measurements are performed with the

phantom static to provide a conventional end-to-end

evaluation of accuracy and then moving (+/- 7 mm

sinusoid) to add separately the effect of motion. A novel

dose-area-histogram, via Matlab, was used to assess dose

coverage of the moving target (GTV and ITV) in the film

plane. Agreement between treatment planning system

(TPS) calculation and measured dose was performed using