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with their email address, profession and hospital
affiliation, while the IP address of the computer from
which the website is accessed is used to track the user’s
geographic location. Google Analytics and Mixpanel were
employed to track the number and duration of each page
view, which was linked to the unique registered user.
Descriptive statistics were reported, including frequency
of repeat use (primary endpoint) defined as the ratio of
users that accessed the website on two different days
divided by the total number of registered users. Users in
the top quintile were further characterized by profession
and geographic location.
Results
eContour has 2,616 registered users, of which most (60%)
are radiation oncologists (1,092 practicing physicians and
459 residents). Other users include dosimetrists (16%),
physicists (9%), radiation therapists (5%), and medical
students (5%). Registered users represent 81 countries,
with the majority (56%) of users located in the US (see
Figure for map). Overall rate of repeat use was 49%, with
residents most likely to return to the site (63%) and
physicists least likely (36%). Repeat users visited the site
on up to 58 different days during the dissemination period,
with residents visiting a mean 6.6 different days and
practicing physicians visiting a mean 5.4 different days.
Users in the top quintile were primarily physicians (69%)
and from the US (67%). Of 33 posted cases in H&N, GI,
GYN, GU and lymphoma, the most frequently viewed
disease site was H&N (8,171 case views) followed by GI
(4,665 case views) and the most frequently viewed cases
were nasopharynx, pre-op rectal, pre-op esophageal,
anal, post-op endometrial, and intact prostate cancer,
each with over 1,000 page views. Users viewed each case
page
for
an
average
of
3.7
minutes.
Conclusion
eContour has a high rate of repeat use especially among
radiation oncologists in the US. Users are most frequently
looking for help contouring GI and H&N cancers, and they
spend fewer than 4 minutes accessing information within
a single case. These preliminary data suggest that
eContour is a resource that fills a need among radiation
oncology professionals. By providing users with updated
contouring guidelines at the point of care, eContour has
the potential to improve contour accuracy and ultimately
impact quality of radiation delivery.
Poster: Clinical track: Other
PO-0752 Birth outcomes in female cancer patients
received radiotherapy: a nationwide population-based
study
W.H. Kao
1
, J.H. Hong
1,2
, C.C. Wang
1,2
, Y.J. Chiang
1
, C.F.
Kuo
3
1
Chang Gung Memorial Hospital, Department of
Radiation Oncology, Taoyuan, Taiwan
2
College of Medicine- Chang Gung University,
Department of Medical Imaging and Radiological
Sciences, Taoyuan City, Taiwan
3
Chang Gung Memorial Hospital, Department of
Rheumatology- Allergy and Immunology-, Taoyuan,
Taiwan
Purpose or Objective
For young female cancer survivors who ever received
radiotherapy, adverse pregnant outcomes are serious
questions not only for themselves but also for their babies.
The purpose of this study was to estimate the risks of
adverse foetal-neonatal outcomes in female cancer
patients received radiotherapy (RT) compared with
women without malignancies.
Material and Methods
We identified 2,350,335 singleton pregnancies using
Taiwan National Health Insurance Database and Taiwan
Birth Registry between 2001 and 2012, of which 607
pregnancies were in female cancer patients with RT. Odds
ratios (ORs) and 95% confidence intervals (CIs) for foetal-
neonatal outcomes were estimated using generalized
estimating equation model adjusted by maternal age,
income, occupation, Charlson comorbidity index,
urbanization, infant sex and birth of year.
Results
From 2001 to 2012, the mean age at pregnancy of female
cancer patients received radiotherapy was 33.5 years old.
There were no significant increasing risks with an adjusted
OR (95% CIs) of 0.50 (0.21-1.21) for stillbirth, 0.75 (0.55-
1.02) for low birth weight, 0.6 (0.45-0.80) for prematurity,
0.97 (0.75-1.27) for small for gestational age, 0.82 (0.65-
1.04) for large for gestational age, 0.98 (0.69-1.38) for
foetal distress, 1.21 (0.92-1.59) for any foetal
abnormalities, 1.36 (0.56-3.29) for central nervous system
malformation, 1.39 (0.62-3.09) for chromosomal
abnormalities, and 1.20 (0.77-1.87) for other/unspecified
abnormalities. The risks of Apgar score < 7 in 1 minute and
in 5 minutes were not significant increased with ORs of
0.71 (0.43-1.18) and 0.62 (0.20-1.94).
Conclusion
For female cancer patients who received radiotherapy,
there were no significant increasing their adverse birth
outcomes compared to women without malignancies.
PO-0753 Radiation therapy and outcome in cancer
patients with acute venous thromboembolism.
J.B. Guy
1
, L. Bertoletti
2
, N. Magné
1
, I. Mahé
3
, C. Font
4
,
O. Sanz
5
, J.M. Martín-Antorán
6
, F. Pace
7
, J. Ramón Vela
8
,
M. Monreal
9
1
Lucien Neuwirth Cancer Institute, Radiation Oncology,
St Priest en Jarez, France
2
CHU Saint-Etienne, Vascular and Therapeutic Medicine,
St Priest en Jarez, France
3
Hopital Louis Mourier, Internal Medicine, Colombes,
France
4
Hospital Clínic de Barcelona, Medical Oncology,
Barcelona, Spain
5
Hospital Universitario de Gran Canaria Dr. Negrín,
Internal Medicine, Las Palmas, Spain
6
Hospital Río Carrión, Haemostasis and Thrombosis,
Palencia, Spain
7
Ospedale San Camillo, Medicina d´Urgenza, Rome, Italy
8
Hospital Universitario Miguel Servet, Internal Medicine,
Zaragoza, Spain
9
Hospital Universitari Germans Trias i Pujol, Internal
Medicine, Barcelona, Spain
Purpose or Objective
There is lack of evidence on the influence of radiation
therapy (RT) on outcome in cancer patients with acute
venous thromboembolism (VTE).
Material and Methods
RIETE (Registro Informatizado Enfermedad Trombo
Embólica) is an ongoing, multicenter, observational
registry of consecutive patients with symptomatic,
objectively confirmed, acute VTE. We used the RIETE
database to compare the rate of VTE recurrences and