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S552

ESTRO 36 2017

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rotations, intrafraction variation, delineation, treatment

and match uncertainties.

When applying online position verification on the prostate,

setup margins for lymph nodes must be 0.19 cm (lateral),

0.73 cm (longitudinal) and 0.57 cm (vertical). When

applying online setup correction on bony structures, setup

margins for the prostate must be 0.25 cm, 0.73 cm and

0.73 cm respectively. Offline setup correction on prostate

resulted in the largest margins for both volumes.

Conclusion

The required setup margin depends on the applied

correction strategy. When applying position verification

on bony structures, larger margins are required for CTV

prostate. When applying position verification on prostate,

larger margins are required for CTV lymph nodes. When

applying these margins clinically, additional margins are

needed to account for rotations, intrafraction variation,

delineation, treatment and match uncertainties.

PO-1010 Investigation of reproducibility of bolus

position based on kV CBCT imaging

E. Dabrowska

1,2

, P. Czuchraniuk

3

, M. Gruda

1

, P.

Kukolowicz

1

, A. Zawadzka

1

1

Maria Sklodowska-Curie Memorial Cancer Center and

Institute of Oncology, Department of Medical Physics,

Warsaw, Poland

2

Faculty of Physics University of Warsaw, Department of

Biomedical Physics, Warsaw, Poland

3

Maria Sklodowska-Curie Memorial Cancer Center and

Institute of Oncology, Department of Radiotherapy,

Warsaw, Poland

Purpose or Objective

On-board kilovoltage (kV) Cone Beam Computed

Tomography (CBCT) imaging is being used predominantly

for patients' positioning to improve the precision and

accuracy of treatment delivery. Moreover, volumetric

CBCT images can be used to evaluate anatomy changes

like tumour shrinking or weight loss as well as changes in

organ volume, deformation or position. Also

reproducibility of accessories used in radiotherapy (the

vacuum bag, bolus position, etc.) can be monitored.

Additionally, the CBCT data set can be used for calculation

of dose distribution. The aim of our study was to analyze

reproducibility of bolus’s position based on kV CBCT

imaging and compare planned and delivered dose

distribution in Clinical Target Volume (CTV).

Material and Methods

For 10 post-mastectomy patients, 35 sarcoma patients and

5 patients with vulva cancer the treatment CT based plans

with bolus were prepared (Eclipse, Varian). For the post-

mastectomy patients the planning CT was acquired with

bolus. For the two other groups the planning CT was made

without bolus. Bolus was drawn in the treatment planning

system. For each patient CBCTs were acquired in the first

and mid fraction and also at the end of treatment. CBCTs

were co-registered offline (automatic rigid match) to the

planning CT. The correctness of boluses positions were

evaluated. Also dose distributions were calculated with

CBCT images and compared with dose distributions

obtained with planning CT. For each patient we took a

photo to document the bolus’s position. To compare dose

distribution calculated on CT and CBCT, a new HU-

density

calibration curve was measured and introduced

into treatment planning system.

CatPhan®503 phantom

was used.

Results

Fusions of CTs and CBCTs showed that there are several

different problems with reproducibility of bolus position.

First of all, bolus generated in TPS will never adhere to

skin like it is presented in TPS, especially when a

irregularity of patient surface is high (Fig. 1a). Moreover,

usually air gaps occur even when there is a smooth surface

of the patients’ body (Fig. 1b). Another problem is the

compatibility of bolus position relative to a field edge (Fig.

1c) which is difficult to reproduce despite it is accurately

described in patient folder. The last two discrepancies

appear regardless if bolus was placed on patient’s skin

during CT scanning or generated in TPS. Preliminary

calculations for 10 soft tissue patients treated with 3D-

CRT plan show, that there is 5,9% ±2,0% a discrepancy

between D98% calculated on CT and CBCT. More advanced

data analysis will be presented for each location

separately, for treatment planning techniques and

information about taken/not taken photo before CT

scanning.

Conclusion

CBCT is a very useful method for accuracy of treatment

planning verification. It allows not only patient position

verification but also for evaluation of bolus positioning

accuracy. Based on CBCT several mistakes influencing

dose deposited to CTV were revealed, what was not

noticeable during a routine verification based on two-

dimensional orthogonal images.

PO-1011 Is it safe to omit a setup correction

validation scan for central lung lesions treated with

SBRT?

M.M.G. Rossi

1

, H.M.U. Peulen

1

, J.S.A. Belderbos

1

, J.J.

Sonke

1