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MRI-guided IMRT: PTV delineation
The combination of 2 problems:
-
unpredictable organ motion
-
substantial tumor regression
resulted in conservative margin recommendations by the Consortium.
PTV margins of 1.5 to 2 cm around the CTV were recommended if good quality daily
soft tissue verification was available during treatment.
A PTV margin of 7 mm around the nodal CTV was agreed upon in line with previous
recommendations in the postoperative cervix cancer setting (
e.g.
, RTOG 0418).
Lim K. et al. Int J Radiat Oncol Biol Phys 2011.