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Results (2)
Sensitivity of 89% & specificity of 97% per LN.
DWI allows the radiation oncologist to very closely approach the true nodal target volume:
Dose-escalation (~ PPV of 91%)?
Organ-sparing (~ NPV of 97%)?
Preliminary results, require confirmation in a larger group…
Nodal staging agreement between imaging results & pathology findings
Modality
Kappa
95% CI
McNemar’s test
CT/TSE
0.56
0.16 - 0.96
P = 0.019
DWI
0.97
0.84 - 1.00
Dirix P. et al. Int J Radiat Oncol Biol Phys 2010.