All reported results for ADC-based nodal staging
Lambrecht M. et al. Expert Rev Anticancer Ther 2010.
Study
Lesion size
(cm)
Mean ADC N+
(x 10
-3
mm
2
/sec)
Mean ADC N-
(x 10
-3
mm
2
/sec)
p-value Threshold
(x 10
-3
mm
2
/sec)
Sens
(%)
Spec
(%)
Wang et al.
Radiology 2001
> 1.0
1.13
±
0.43
1.56
±
0.51
0.002
1.22
84
91
Sumi et al.
J Neuroradiol 2003
> 1.0
0.41
±
0.11
0.30
±
0.06
< 0.01
0.4
52
97
Abdel Razek et al.
Eur Radiol 2006
0.9 – 1.5
1.09
±
0.11
1.64
±
0.16
< 0.04
1.38
98
88
Sumi et al.
AJR 2006
> 1.0
1.17
±
0.45
0.63
±
0.10
< 0.001 0.74
86
94
Vandecaveye et al.
Radiology 2009
0.4 – 1.5
0.85
±
0.27
1.19
±
0.22
< 0.0001 0.94
84
94
de Bondt et al.
Neuroradiology 2009
0.5 – 3.0
0.85
±
0.19
1.2
±
0.24
< 0.05
1.0
92
84
Holzapfel et al.
Eur J Radiol 2009
> 1.0
0.78
±
0.09
1.24
±
0.16
< 0.05
1.02
100
87
Perrone et al.
Eur J Radiol 2011
NA
0.85
1.45
< 0.01
1.03
100
93