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All reported results for ADC-based nodal staging

Lambrecht M. et al. Expert Rev Anticancer Ther 2010.

Study

Lesion size

(cm)

Mean ADC N+

(x 10

-3

mm

2

/sec)

Mean ADC N-

(x 10

-3

mm

2

/sec)

p-value Threshold

(x 10

-3

mm

2

/sec)

Sens

(%)

Spec

(%)

Wang et al.

Radiology 2001

> 1.0

1.13

±

0.43

1.56

±

0.51

0.002

1.22

84

91

Sumi et al.

J Neuroradiol 2003

> 1.0

0.41

±

0.11

0.30

±

0.06

< 0.01

0.4

52

97

Abdel Razek et al.

Eur Radiol 2006

0.9 – 1.5

1.09

±

0.11

1.64

±

0.16

< 0.04

1.38

98

88

Sumi et al.

AJR 2006

> 1.0

1.17

±

0.45

0.63

±

0.10

< 0.001 0.74

86

94

Vandecaveye et al.

Radiology 2009

0.4 – 1.5

0.85

±

0.27

1.19

±

0.22

< 0.0001 0.94

84

94

de Bondt et al.

Neuroradiology 2009

0.5 – 3.0

0.85

±

0.19

1.2

±

0.24

< 0.05

1.0

92

84

Holzapfel et al.

Eur J Radiol 2009

> 1.0

0.78

±

0.09

1.24

±

0.16

< 0.05

1.02

100

87

Perrone et al.

Eur J Radiol 2011

NA

0.85

1.45

< 0.01

1.03

100

93