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Integration sites of HPV16 in HNSCC

TP63: a member of

the p53 family

RAD51B: DNA

damage repair

,

tumor suppressor,

decrease

chemosensitivity

Kruppel-like factor 5

(KLF5): zinc finger

,

radiation sensitivity

-

-

containing transcription

factor, maintain

pluripotency in stem cells

CD275 (PD-L1, B7-H1): Immune

h k i t

t i

Joseph D. Khoury et al. J. Virol. 2013;87:8916-8926

c ec po n pro e n