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Acute mucositis: prevention
Palifermin
- is a recombinant truncated form of human keratinocyte growth
factor (KGF), a member of the fibroblast growth factor family, that
acts on epithelial tissue to exert a cytoprotective effect against
chemotherapy- and radiation therapy–induced mucosal injury
- approved for prophylaxis against severe mucositis among patients
undergoing HSCT for hematologic malignancies.
Trotti et al. JCO 2009