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Acute mucositis: low level laser
N= 75 , Low-level laser versus placebo, chemoradiation
d ¾ iti
t i ifi
tl d
d t
k 4 ( 0 08)
- gra e mucos s no s gn can y ecrease a wee p= .
- less treatment interruption due to mucositis: 6 vs 0 (p= 0.02)
N= 94 , Low-level laser versus placebo, chemoradiation
- grade ¾ mucositis decreased: 48% vs 6.4 % (p<0.001)
- less treatment interruption, less pain, less gastrostomia, better
Q&L
N= 220 , Low-level laser versus placebo, chemoradiation
better quality of life (FACT HN questionnaire)
-
-
- significant reduction in severe mucositis, opoid analgesic, and
parenteral nutrition
Gautam AP et al. Supportive care Cancer 2013
Gouvêa de Lima et al. Int J Radiat Oncol Biol Phys 2010
Antunes et al. Radiotherapy Oncol 2013