1732-1733 / 2351
Systemic skin toxicity with anti-EGFR
Antiacne or antirosacea (erythromycin or clindamycin gel)
Mild
Topical corticosteroids
Antihistaminic if itching
Oral tetracycline: i.e. minocycline 100 mg/day (pustule)
Severe
Paronychia: hygiene, Potassium permanganate soak, topic steroids and antibiotics, silver
nitrate
Segaert S, Van Cutsem E. Ann Oncol 2005