1740-1741 / 2351
Anemia and erythropoietin: Cochrane database
Meta-analysis of five studies with a total of 1397 patients
Radiation therapy versus radiation therapy + EPO
Significantly worse overall survival for RT plus EPO was observed
compared to RT alone
odds ratio 0.73; (95% CI 0.58 to 0.91); p = 0.005
However, the target hemoglobin concentration was higher than
recommended in four of the five trial and may have had a significant role
Lambin P Cochrane Database Syst Rev 2009