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Issues related with chemotherapy

Cisplatin

Nephrotoxicity

Peripheral neuropathy

Ototoxicity

Less hematotoxicity than carboplatin

Conditions for cisplatin administration

Creatinine Clearance > 60 ml/min

N t hil

t 1000/ 3

eu rop coun >

mm

Platelet count > 75 000/mm3

Although not cardiotoxic be sure that the patients has a heart function

,

compatible with administration of 4 liter of saline solution in less than

24 hours