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Issues related with chemotherapy
Cisplatin
Nephrotoxicity
Peripheral neuropathy
Ototoxicity
Less hematotoxicity than carboplatin
Conditions for cisplatin administration
Creatinine Clearance > 60 ml/min
N t hil
t 1000/ 3
eu rop coun >
mm
Platelet count > 75 000/mm3
Although not cardiotoxic be sure that the patients has a heart function
,
compatible with administration of 4 liter of saline solution in less than
24 hours