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Between 40-60% of patients will relapse in the head and neck area without

distant metastases.

Imaging sometimes difficult due to the morphological modification of the local

tissues induced by previous surgery and/or (chemo)radiation.

The differential diagnosis includes radionecrosis, infection,and scar from

previous treatment(s).

Effort should be made to obtain pathological confirmation

PET/scan

Pivot et al, Oncology, 2001

Diagnosis