•
Between 40-60% of patients will relapse in the head and neck area without
distant metastases.
•
Imaging sometimes difficult due to the morphological modification of the local
tissues induced by previous surgery and/or (chemo)radiation.
•
The differential diagnosis includes radionecrosis, infection,and scar from
previous treatment(s).
•
Effort should be made to obtain pathological confirmation
•
PET/scan
Pivot et al, Oncology, 2001
Diagnosis