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The differential diagnosis must be made taking with a second primary cancer,

particularly if curative treatment can be proposed.

The rate of synchronous pulmonary tumors is around 4%

The overall incidence of metachronous second primary cancers is 2% per year.

Lung metastases: surgery ?

Ghosh et al Head Neck 2009, Laccourreye et al Ann Otol Rhinol Laryngol. 2002