2050-2051 / 2351
Randomized trials mono vs polychemotherapy
Jacobs et al JCO 2002, Clavel et al Ann Oncol 1994, Forastiere et al JCO 1992
Regimens
N ORR
(%)
Median survival
(months)
Cisplatin/5-FU
vs
Cisplatin
vs
5-FU
249
32%
17%
13%
5.5
5
6.1
Cisplatin/methotrexate/
bleomycine/vincristine
vs
Cisplatin/5-FU
vs
Cisplatin
382
34%
31%
15%
8.2
6.2
5.3