226-227 / 2351
I
II
II
I
V
VI
DIAGNOSTIC WORK-UP
SENTINEL NODE BIOPSY
Minimally invasive
Little morbidity
Negative predictive value 90-95%
Additional second stage surgery
Needed in case of pN+(sn)
Admission needed
Injection of radioactive tracers
Intensive labor
In T1-T2 cN0 carcinoma of OC or OP
successful staging in 95-100% of cases
<5% of regional recurrence in patients staged pN0 (sn)
Stoeckli et al., Eur Arch Otorhinolaryngol, 2009
In comparison, routine elective ND in cN0 SCC carries
an approximately 1.6–10% rate of regional recurrence
Schmitz et al., Eur Arch Otorhinolaryngol, 2009
Iype et al. Oral Oncol, 2008
Buck et al., Head Neck, 2008
mercoledì 29 giugno 16