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FNAC
EFFICIENT, MINIMALLY INVASIVE, AND COST-EFFECTIVE
DIAGNOSTIC METHOD WITH NEGLIGIBLE RISK OF
SEEDING TUMOR CELLS ALONG THE NEEDLE TRACK
FOR METASTATIC LESIONS:
SENSITIVITY: 83-97%
SPECIFICITY: 91-100%
SCC
ACCOUNTS FOR
53-77%
THE REMAINING ARE ADENOCARCINOMA AND
UNDIFFERENTIATED CARCINOMA
Gourin et al., Laryngoscope 2000
Layfield, Diagn Cytopathol 2007
Cianchetti et al., Laryngoscope 2009
BUT....IN
CYSTIC METASTASES
, A FALSE-NEGATIVE RATE OF 42% WITH FNAC IS REPORTED WITH
SENSITIVITY RANGING FROM 33% TO 50%, BECAUSE IT CAN BE DIFFICULT TO DISTINGUISH CYSTIC
METASTASES FROM BENIGN BRANCHIAL CYSTS, ABSCESS, OR TUBERCULOSIS
Open cervical lymphnode biopsy is indicated
only
when
repeated FNAC followed by a core-needle-
biopsy are nondiagnostic or in patients with masses
clinically and histologically suspicious for lymphoma
IDENTIFICATION OF THE PRIMARY TUMOR
mercoledì 29 giugno 16