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EORTC 22791

Hyperfractionation

356 pts. T2-T3 N0-N1 oropharynx

Loco-regional control

Late effects

Horiot et al. Radiother. Oncol. 1992

Improved Terapeutic Ratio:

Increase in tumor control with same late morbidity

p = 0.02

n.s.