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96

JCPSLP

Volume 18, Number 2 2016

Journal of Clinical Practice in Speech-Language Pathology

allowing for the interpretation of data from large bodies of

information (Petticrew & Roberts, 2006).

Predictive factors for stuttering

treatment

Findings from systematic reviews

There is much to learn from investigating the predictive

factors of stuttering treatment outcomes. With improved

measures of treatment outcomes encompassing the impact

of stuttering on an individual’s quality of life, as well as the

more reliable identification and measurement of relevant

client and clinician factors, it may be possible one day to

develop predictive models of treatment success.

Previous systematic reviews of stuttering treatment

include one by Bothe, Davidow, and Bramlett (2006). They

conducted a qualitative systematic review of behavioural,

cognitive, and related approaches to stuttering therapy

across a range of age groups. The prolonged speech

approach, treatment targeting self-management, and

treatment using response contingencies were found to

have the strongest evidence for adults who stutter (AWS).

For early stuttering, the authors concluded response-

contingent-based therapies had the strongest evidence.

Herder, Howard, Nye, and Vanryckeghem (2006)

reported results from a systematic review and meta-

analysis of behavioural stuttering treatments and concluded

that treatments resulted in positive therapeutic gains, but

there was no one treatment approach that was significantly

better than the others. Subsequently, a systematic review

by Nye and colleagues (2013) reported that the current

best evidence for children who stutter up to 6 years of age

was the Lidcombe Program (LP) developed by Onslow

and colleagues. Of these systematic reviews of treatment

in stuttering, none specifically addressed predictive factors

of treatment outcomes. Nevertheless, the importance of

finding out more about predictive factors was recognised

(Herder et al., 2006; Nye et al., 2013). Nye et al. (2013)

further acknowledged that there were limited data available

to make any useful conclusions.

Herder et al. (2006) noted a lack of understanding of

how each factor or sets of factors may impact on treatment

outcome. Interestingly, they concluded that differences in

the effectiveness of intervention approaches were unlikely

due to the nature of the intervention strategies themselves

or to participant characteristics. Instead they hypothesised

that clinician impact could have played a role, stating that

“it might well be that the clinician represents a helping

individual who is perceived to have the knowledge and skills

to bring about a change in the speech behavior of a person

who stutters” (Herder et al., 2006, p. 70).

Adults who stutter

Results from the systematic reviews demonstrate that

treatment for stuttering is generally beneficial. However,

predicting which individuals will benefit most, as well as

knowing how to support those who may have higher risk of

regression, is a pivotal for clinicians prior to commencing

intervention. The potential to relapse is of interest and

concern in the provision of treatment to AWS, with up to

72% of adults relapsing post-treatment (Craig, 1998).

Relapse is defined as “stuttering to a degree which was not

acceptable to yourself for at least a period of one week”

(Craig, 1998, p. 3).

Stuttering severity

The definition of a predictive factor provided at the

beginning of this review stated that it relates to client

Age at onset

Yairi et al. (1996), in comparing groups of children who

recovered from stuttering with those whose stuttering

persisted, reported that children who continued to stutter

started stuttering 5 to 8 months later (onset at 39 months

of age) than those who recovered (onset from 30 to 33

months of age).

Time since onset

The time since onset of stuttering has been found to be a

prognostic factor for persistent stuttering, with the risk of

persistent stuttering being greater in individuals who have

been stuttering for more than one year than in those who

have not (Ambrose & Yairi, 1999).

Neurology

Chang and Ludlow (2010) reported further neurological

data to identify factors of persistence. Specifically, children

who had a persistent stutter had reduced white matter

integrity in the left hemisphere areas of the brain involved in

speech compared to those who recovered.

Language ability

There are inconsistent findings for status of speech and

language skills in predicting persistence of stuttering. For

example, Yairi et al. (1996) reported that better speech and

language skills may be related to recovery from stuttering,

whereas Watkins and Yairi (1997) found that children whose

stuttering persisted had typical to advance language skills.

Additional factors

Other behavioural factors that have been found to be

different between children with persistent stuttering and

children who recovered include differences in second

formant transitions (Subramanian, Yairi, & Amir, 2003),

higher variability of articulation rate for persistent stuttering

(Kloth, Kraaimaat, Janssen, & Brutten, 1999), and poorer

phonological and speech production abilities for persistent

stuttering (Spencer & Weber-Fox, 2014). Howell and Davis

(2011) found that symptom severity, as measured by the

Stuttering Severity Index, of children who stutter at 8 years

old was the only significant factor that was able to predict

persistence of stuttering in the teenage years using logistic

regression analysis. However, Yairi and colleagues (1996)

did not find that initial stuttering severity predicted

persistence in their study of younger children (under 6

years).

Interpreting risk and prognostic factors

In summary, common prognostic factors of stuttering onset

and of persistent stuttering include positive family history of

stuttering and age. An older child has less risk of stuttering

onset, though if a child is older when onset does occur, the

risk for the stutter to be persistent is higher. Additional

factors associated with persistent stuttering (i.e.,

behavioural factors) have been identified; however, caution

is required when interpreting such findings. For example,

replication of findings is needed to establish reliable

indicators of persistence, since current results are based

predominantly on single or few studies, with many having

small sample sizes (e.g., Chang et al., 2005,

n

= 14). A

number of studies are retrospective in design and it is

recommended that prospective studies are more

appropriate to answer questions of prognosis (Moons et al.,

2009). While there have been comprehensive reviews of

prognostic factors of stuttering onset and persistence, none

were systematic reviews. A systematic review would

synthesis and evaluate available information on this topic