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8 Maximum Time-to-Signal

No maximum time.

Approved by the AOAC Stakeholder Panel on Infant Formula and Adult Nutritionals (SPIFAN). Final Version Date: April 5,

2011. Effective Date: June 29, 2011.

Table 1. Method performance requirements

a

Analytical range

0.50–300

b

Limit of detection

(LOD)

≤0.10

b

Limit of quantitation

(LOQ)

≤0.50

b

Repeatability (RSD

r

)

0.50–21.5

b

≤11%

>21.5

b

≤7%

Recovery

90–110%

Reproducibility (RSD

R

)

0.5–21.5

b

≤32%

>21.5

b

≤16%

a

Concentrations apply to (

1

) “ready-to-feed”

liquids “as is”; (

2

) reconstituted powders (25 g

into 200 g water); and (

3

) liquid concentrates

diluted 1:1 by weight.

b

µg/100 g expressed as folic acid in reconstituted

final product.