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VI.
Head and Neck
Cockerill CC, Gross BC, Contag S, et al. Pediatric malignant salivary gland tumors: 60 year
follow up.
Int J Pediatr Otorhinolaryngol
. 2016; 88:1-6. EBM level 4......................159-164
Summary
: This article reviews the presentation, treatments, and outcomes of pediatric
patients with salivary gland malignancies. A total of 56 patients were identified. The
majority of patients presented with a painless mass without facial nerve weakness at a mean
age of 14.1 years. Most of the tumors originated in the parotid gland (88%), with 5% in the
submandibular gland and 7% in the minor salivary glands. The most common histologies in
the major salivary glands were mucoepidermoid carcinoma and acinic cell carcinoma. Most
were of low tumor grade, presenting at an early stage, and a majority were treated with total
parotidectomy without adjuvant therapy. The rate of local recurrence was low (27%). Most
patients with major salivary gland malignancies (85%) were alive with no evidence of
disease. In patients with minor salivary gland malignancies, the recurrence rate was 75%,
and the rate of distant metastasis and death was 50%.
Dermody S, Walls A, Harley EH Jr. Pediatric thyroid cancer: an update from the SEER
database 2007-2012.
Int J Pediatr Otorhinolaryngol
. 2016; 89:121-126. EBM
level 4..............................................................................................................................165-170
Summary
: This article describes a query of the SEER database to provide an update on the
incidence, disease-specific survival, and treatment modalities of pediatric patients with
thyroid cancer. A total of 1723 pediatric patients were identified with thyroid cancer between
2007-2012, giving an average age-adjusted rate of malignancy of 0.59 per 100,000 patients.
Fifteen-year disease-specific survival is greater than 95% for the most common thyroid
carcinoma subtypes, excluding medullary carcinoma, with appropriate treatment modalities
(surgery with and without adjuvant radiation).
Dremmen MH, Tekes A, Mueller S, et al. Lumps and bumps of the neck in children-
neuroimaging of congenital and acquired lesions.
J Neuroimaging
. 2016; 26(6):562-580.
EBM level 4....................................................................................................................171-189
Summary
: This article reviews the imaging characteristics of the most common congenital
and acquired neck masses in the pediatric population. The article covers congenital masses
such as thyroglossal duct anomalies, branchial apparatus anomalies, laryngeal anomalies, and
vascular anomalies, as well as acquired masses such as ranula, fibromatosis colli, sialadenitis,
and lymphadenitis. Ultrasound, MRI, and CT scan can be used along with the patient’s age,
clinical history, and examination results to provide an accurate diagnosis of pediatric neck
masses.