147 / 1068
5-year
Outcome
Postoperative
CRT
Preoperative
CRT
p
Local recurrences
13%
6%
.006
Sphincter
preservation*
19%
39%
.004
CAO/ARO/AIO-94
Acute toxicity
grade 3-4
40%
27%
.001
Distant
recurrences
38%
36%
.84
Overall survival
76%
74%
.80
Sauer R. et al., N Engl J Med 2004
*Deemed to require APR