151 / 1068
TME-
Quality
Local Recurrence Rate (3y)
N
RT + TME
TME
HR
„Poor
“
Defects to
Muscularis propria
154
(13%)
10% 16% 2.0
MRC-CR07 – Local Recurrences
„Moderat
“
Intra-mesorectal
excision
398
(34%)
4%
10% 2.8
„Optimal
“
Mesorectal
excision
604
(52%)
1%
7% 4.5
Sebaq-Montefiori D. et al., Lancet 2009
Similar results: Dutch TME Trial, Kapiteijn E, N Engl J Med 2001