154 / 1068
T1-3 N
any
5x5 Gy
+ Surg
vs
Surg alone
Swedish Trial
n=1168
Local Recurrences
@ 13 years
Dutch Trial
n=1861
Local Recurrences
@ 10 years
British Trial
n=1350
Local Recurrences
@ 5 years
9% vs 26%
(p<.001)
Overall Survival (13y)
38% vs 30%
(p=.008)
5% vs 11%
(p<.001)
Overall Survival (10y)
48% vs 49%
(n.s.)
5% vs 12%
(p<.001)
Overall Survival (5y)
70% vs 68%
(n.s)
Fokesson et al., J Clin Oncol 2005 van Gijn et al., Lancet Oncol 2011 Sebag-Montefiore et al., Lancet 2009