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The TIMING Trial

RT 50.4 Gy/1.8Gy

5-FU 225 mg/m

2

T

M

E

6 wks

Group

1

mFOLFOX6

2#, q15

RT 50.4 Gy/1.8Gy

5-FU 225 mg/m

2

4 wks

4 wks

Group

2

T

M

E

Garcia-Aquilar J et al, Lancet Oncol 2015

mFOLFOX6

4#, q15

RT 50.4 Gy/1.8Gy

5-FU 225 mg/m

2

4 wks

4 wks

Group

3

mFOLFOX6

6#, q15

RT 50.4 Gy/1.8Gy

5-FU 225 mg/m

2

4 wks

4 wks

Group

4

T

M

E

T

M

E