The TIMING Trial
RT 50.4 Gy/1.8Gy
5-FU 225 mg/m
2
T
M
E
6 wks
Group
1
mFOLFOX6
2#, q15
RT 50.4 Gy/1.8Gy
5-FU 225 mg/m
2
4 wks
4 wks
Group
2
T
M
E
Garcia-Aquilar J et al, Lancet Oncol 2015
mFOLFOX6
4#, q15
RT 50.4 Gy/1.8Gy
5-FU 225 mg/m
2
4 wks
4 wks
Group
3
mFOLFOX6
6#, q15
RT 50.4 Gy/1.8Gy
5-FU 225 mg/m
2
4 wks
4 wks
Group
4
T
M
E
T
M
E