170 / 1068
50.4 Gy
5-FU/Ox
5x5 Gy
FOLFOX
P-value
Number of pts
254
261
R0 resection (%)
71
77
.07
pCR (%)
12
16
.21
Acute tox grade 1+2/ 3+4 / 5
50 / 21 / 3
60/ 23 / 1
.006
Polish Trial II
Postop complication
25
29
.18
Local Failure @3y (%)
21
22
.82
Disease-free Survival @ 3y (%)
52
53
.85
Overall Survival @ 3y (%)
65
73
.046
Med. F/u:
35 mo
Bujko et al., ASCO GI 2016