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First interim analysis

after 300 pts

(1998-2005)

5x5 Gy

immediate

TME

5x5 Gy

delayed

TME

25x2 Gy

delayed

TME

Number of pts

118

120

65

Stockholm III Trial

Severe RT-induced Tox

(hospital admission, %)

0

4.2

5

Postop. Complications (%)

Reoperations (%)

Anastomotic leak (%)

47

10

13

40

11

11

32

5

4

Petterssons et al., Br J Surg 2010