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The Royal Marsden
Measuring size of nodes worsens results – overstaging
and overtreatment of low risk patients
•
node positive if either irregular border or
mixed signal intensity.
•
Metastases demonstrated in 51/56 nodes
(91%, 95% CI 81% to 96%) with either an
irregular border or a mixed intensity signal.
•
only 9/225 nodes (4%, CI 2.1% to 7.4%) with
smooth borders and a uniform signal
contained metastases irrespective of size.
•
Size of node bears no relationship to
malignant risk
Brown et al Radiology 2003