425 / 1068
The Royal Marsden
Conclusions restaging MRI – prognostic
and predictive imaging biomarkers for
DFS
– Persistent ymrEMVI seen twice as frequently as
ypEMVI and independent risk factor for poor DFS
– mrTRG 1-2 has similar DFS and OS as pCR but seen 4
times more frequently than pCR (prospective
randomised trial data)
– mrTRG1-2 represents a population of patients highly
likely to have no viable tumour hence suitable for MRI
monitoring in deferral of surgery trial
– Patients will be randomised to have an mrTRG defined
treatment strategy in the TRIGGER trial – do please
join us!