466 / 1068
Therapeutic ratio (II)
Easy to interpret: this is the cure rate in percentage point per
percentage point patients with toxicity
Very sensitive to statistical uncertainty for small values of NTCP
NTCP
TCP
R
=
Face validity?
TCP=40% and NTCP=1%
⇒
R=40
TCP=80% and NTCP=2%
⇒
R=40