For resectable cancers pre-Operative Radiotherapy
There are 2 preoperative adiation regimens accepted as
standard:
•
Short course (5 X 5 Gy delivered over 1 week) with
surgery performed ideally within the next 5 days
•
conventionally fractionated chemoradiation 45-50.4Gy
(25-30 fractions of 1.8 or 2 Gy over 5-6 weeks) with
surgery performed 4 to 10 weeks after treatment
completion.
• (Folkesson et al, JCO 23, 24: 5644 – 5650, Kapiteijn
et al
,
NEJM, 345 (9), 638-646, 2001, David Sebag-Montefiore
et
al,
Lancet. 2009 Mar 7;373(9666):811-20)