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Radiotherapy is generally regarded as a cell death

inducing technique.

Radiation also induces inflammatory or anti-

inflammatory reactions depending on dose and

fractionation

Reichl B, et al. DEGRO practical guidelines for radiotherapy of non-malignant disorders: Part

I: physical principles,radiobiological mechanisms, and radiogenic risk. Strahlenther Onkol

2015;191(9):701-9.

Shahabi V, et al. Immune-priming of the tumor microenvironment by radiotherapy: rationale

for combination with immunotherapy to improve anticancer efficacy. Am J Clin Oncol

2015;38(1):90-7.