•
Radiotherapy is generally regarded as a cell death
inducing technique.
•
Radiation also induces inflammatory or anti-
inflammatory reactions depending on dose and
fractionation
Reichl B, et al. DEGRO practical guidelines for radiotherapy of non-malignant disorders: Part
I: physical principles,radiobiological mechanisms, and radiogenic risk. Strahlenther Onkol
2015;191(9):701-9.
Shahabi V, et al. Immune-priming of the tumor microenvironment by radiotherapy: rationale
for combination with immunotherapy to improve anticancer efficacy. Am J Clin Oncol
2015;38(1):90-7.