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Viani

using this model, we could hypothetically

predict that a BED of approximately 68.8 Gy

10

would need to be delivered to patients with

localized rectal cancer to achieve 100% local

control with surgery

using a high dose for fraction of 5 Gy to achieve

a BED Gy

10

of 68.8 would require nine fractions,

resulting in a BED of 117 Gy

3

.