Jakobsen A 2012: endpoints
Endpoint
CRT
+brachytherapy
boost n=90
Standard CRT
n= 92
P value
pCR
18%
NS
R0 Resection 99%
90%
P= 0.03
Major
response
TRG 1 and 2
44% (35/80) 28% (23/82) P= 0.04