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Contact therapy (Papillon)

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Dose prescribed at the surface of the tumor

- Steep fall-off of dose with depth

44% at 5 mm

25% at 10 mm

- Delivery of large doses per fraction (approximately 30 Gy per fraction)

- Gradual destruction of exophytic tumours layer per layer in a few fractions

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3-4 fractions (90-120 Gy)

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4-6 weeks overall treatment time

Gérard et al. Int J Radiat Oncol Biol Phys. 1996;34(4):775–83.

Papillon et al. Int J Radiat Oncol Biol Phys. 1989;17(6):1161-9

Coatmeur et al. Radiother Oncol 2004;70(2):177–82.