Contact therapy alone
Papillon:
- 312 patients between 1951 – 1984
- T1 and favorable T2 rectal adenocarcinoma
- 5Y local control: 90 %
- 5Y overall survival: 75 %
- Low morbidity
Mendenhall:
- Early stage rectal adenocarcinoma
- 20 patients contact therapy vs. 45 patients local excision +EBRT
- 5Y LC 80 vs. 86%
Papillon et al. Int J Radiat Oncol Biol Phys. 1989;17(6):1161-9
Mendenhall et al. J Clin Oncol 1997;15(10):3241-3248