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3. HDR-EBT – Boost after EBRT

Late results (published in 2014)

- No benefit on late outcome

(OS, PFS, LC, distant mets)

- Improved tumor regression

does not lead to relevant

clinical benefit when high-

quality surgery is performed

Appelt et al. Int J Radiat Oncol Biol Phys. 2014;90(1):110–8.